Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 7/20 | 0.83 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.65 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063354 | 0.94 | AKR1B1 (0.82) | AKR1B1AKR1A1PTGDR2AKR1B10PKM | |
| SCHEMBL5459444 | 0.93 | AKR1B1 (0.77) | AKR1B1AKR1A1PTGDR2AKR1B10MMP2 | |
| SCHEMBL7067035 | 0.92 | AKR1B1 (0.75) | AKR1B1AKR1A1PTGDR2AKR1B10MMP2 | |
| SCHEMBL7065285 | 0.92 | AKR1B1 (0.84) | AKR1B1AKR1A1PTGDR2AKR1B10TSHR | |
| SCHEMBL5462608 | 0.92 | AKR1B1 (0.75) | AKR1B1AKR1A1PTGDR2AKR1B10PKM | |
| SCHEMBL7063287 | 0.92 | AKR1B1 (0.78) | AKR1B1AKR1A1PTGDR2AKR1B10PKM | |
| SCHEMBL7065032 | 0.91 | AKR1B1 (1.00) | AKR1B1AKR1A1PTGDR2AKR1B10L3MBTL1 | |
| SCHEMBL5466063 | 0.90 | AKR1B1 (0.72) | AKR1B1AKR1A1PTGDR2PKMMMP2 | |
| SCHEMBL7064157 | 0.90 | AKR1B1 (0.72) | AKR1B1AKR1A1PTGDR2 | |
| SCHEMBL5466139 | 0.89 | AKR1B1 (0.70) | AKR1B1AKR1A1PTGDR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161631-A1 | Substituted Phenoxyacetic Acids | PHARMACIA & UPJOHN COMPANY | 2007-07-12 | — | — | US | disclosed |
| US-20070161631-A1 | Substituted Phenoxyacetic Acids | PHARMACIA & UPJOHN COMPANY | 2007-07-12 | — | — | US | disclosed |
| US-7189749-B2 | Substituted phenoxyacetic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189749-B2 | Substituted phenoxyacetic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2007-03-13 | — | — | US | disclosed |
| US-20030036558-A1 | Substituted phenoxyacetic acids | THE INSTITUTES OF PHARMACEUTICAL DISCOVERY LLC. | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161631-A1 | Substituted Phenoxyacetic Acids | SLC5A2, GPR119, SLC5A1 | AKR1B1 708/4885AKR1A1 791/4885PTGDR2 281/4885 |
| US-20030036558-A1 | Substituted phenoxyacetic acids | SLC5A2, GPR119, SLC5A1 | AKR1B1 708/4885AKR1A1 791/4885PTGDR2 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.