SCHEMBL7066292

SCHEMBL7066292

C[Hf](c1ccccc1)(c1ccccc1)(C1C=Cc2ccccc21)(C1C=Cc2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7066358 0.98 KDM4E (0.31)
SCHEMBL7066990 0.72
SCHEMBL7066304 0.72
SCHEMBL7520595 0.70 HTR6 (0.33) SIGMAR1
SCHEMBL6916186 0.70
SCHEMBL9420397 0.67 HTR2A (0.33) SIGMAR1
SCHEMBL19630560 0.63 HTR2A (0.39) SIGMAR1GPR3
SCHEMBL29386036 0.63 HTR2A (0.39) SIGMAR1GPR3
SCHEMBL8160813 0.62 HTR6 (0.33) SIGMAR1
SCHEMBL8159013 0.61 MEN1 (0.34) SIGMAR1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530908-B2 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 2003-06-04 EP disclosed
EP-0530908-B1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1999-04-21 EP disclosed
EP-0530908-A1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1993-03-10 EP disclosed