Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.36 |
| ▸ | SELE | P16581 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066025 | 0.96 | MAPT (0.40) | LDHAEDNRAKDM4EMAPK1NPSR1 | |
| SCHEMBL7070060 | 0.93 | MAPT (0.40) | LDHAEDNRAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7069283 | 0.93 | ICAM1 (0.39) | LDHAEDNRAKDM4EMAPK1NPSR1 | |
| SCHEMBL7066779 | 0.91 | ICAM1 (0.39) | LDHAEDNRAKDM4EMAOBMAPT | |
| SCHEMBL7070398 | 0.91 | MAPT (0.42) | KDM4ENPSR1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL7069531 | 0.91 | LDHA (0.40) | LDHAEDNRAKDM4EMAPK1NPSR1 | |
| SCHEMBL7071902 | 0.90 | PPARG (0.43) | LDHAEDNRAKDM4EMAOBMAPT | |
| Hydrochloric Acid SCHEMBL7066556 | 0.89 | PPARG (0.42) | LDHAEDNRAKDM4EMAOBMAPT | |
| SCHEMBL7069467 | 0.89 | MAPT (0.39) | LDHAEDNRAKDM4ENPSR1MAOB | |
| SCHEMBL7070604 | 0.88 | MAPT (0.44) | KDM4EMAPK1MAOBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | MITSUI CHEMICALS, INC. (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1266888-A1 | QUINOLINE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | PPARG, PPARD, PPARA | LDHA 2228/4885EDNRA 2968/4885KDM4E 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.