Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886251 | 0.92 | APP (0.40) | APPCYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL9195419 | 0.91 | CTSC (0.40) | APPCYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL7066941 | 0.90 | ALDH1A1 (0.40) | MEN1KMT2AFFAR4ALDH1A1HPGD | |
| SCHEMBL7508869 | 0.87 | AKR1C3 (0.43) | APPCYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL7065829 | 0.86 | MEN1 (0.35) | APPCYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL7507920 | 0.83 | AKR1C3 (0.44) | APPCYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL10874182 | 0.82 | KMT2A (0.48) | MEN1KMT2AAKR1C1FFAR4 | |
| SCHEMBL9763553 | 0.82 | MEN1 (0.39) | APPCYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL10723391 | 0.82 | MEN1 (0.41) | APPCYP3A4CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL9764010 | 0.81 | MEN1 (0.38) | APPCYP3A4CYP2C19CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673986-B1 | Active matrix type liquid crystal display apparatus | HITACHI LTD (JP) | 2003-06-04 | — | — | EP | claimed |
| EP-1070753-A2 | Liquid crystal compounds and their use in active matrix type liquid crystal display devices | HITACHI, LTD. (JP) | 2001-01-24 | — | — | EP | claimed |
| EP-0673986-A2 | Active matrix type liquid crystal display apparatus | HITACHI, LTD. (JP) | 1995-09-27 | — | — | EP | claimed |
| EP-0673986-B1 | Active matrix type liquid crystal display apparatus | HITACHI LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-1070753-A2 | Liquid crystal compounds and their use in active matrix type liquid crystal display devices | HITACHI, LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0673986-A2 | Active matrix type liquid crystal display apparatus | HITACHI, LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |