SCHEMBL7066539

SCHEMBL7066539

CC(c1ccc(Cl)cc1)N1CCC1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 3/20 0.44
HSD11B1 P28845 2/20 0.42
OPRM1 P35372 2/20 0.42
OPRD1 P41143 2/20 0.42
OPRK1 P41145 2/20 0.42
OPRL1 P41146 2/20 0.42
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 1/20 0.40
NOTUM Q6P988 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
DPP4 P27487 1/20 0.39
DPP7 Q9UHL4 1/20 0.39
CCR1 P32246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7065814 0.86 TSHR (0.41) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL7064462 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL5685802 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL8017580 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL5685795 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL5688789 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL5685799 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL5701978 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL5685648 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1
SCHEMBL5685658 0.86 CYP2D6 (0.47) HSD11B1OPRM1OPRD1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed