SCHEMBL7066835

SCHEMBL7066835

c1ccc(NCCP(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MAPT P10636 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.47
HRH3 Q9Y5N1 1/20 0.41
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
DRD4 P21917 1/20 0.35
TDP1 Q9NUW8 3/20 0.35
CTSD P07339 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
DPP7 Q9UHL4 1/20 0.34
MAN1B1 Q9UKM7 1/20 0.34
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL951191 0.79 SIGMAR1 (0.39) MAPTDRD4TDP1CYP3A4MAOA
SCHEMBL1465693 0.78 SIGMAR1 (0.35) ALDH1A1MAPTDRD4TDP1CYP3A4
SCHEMBL27841143 0.78 CYP3A4 (0.47) ALDH1A1TDP1CYP3A4
Hydrochloric Acid SCHEMBL1465772 0.77 SIGMAR1 (0.38) MAPTDRD4TDP1CYP3A4MAOA
SCHEMBL31026596 0.77 SIGMAR1 (0.38) MAPTDRD4TDP1CYP3A4MAOA
SCHEMBL346711 0.77 TDP1 (0.41) DRD4TDP1CYP3A4MAOAMEN1
SCHEMBL9806648 0.77 CYP3A4 (0.41) ALDH1A1MAPTTDP1CYP3A4MAPK1
SCHEMBL29505333 0.77 CYP3A4 (0.41) ALDH1A1MAPTTDP1HSD17B10CYP3A4
SCHEMBL666371 0.77 CYP3A4 (0.41) ALDH1A1MAPTTDP1CYP3A4MAPK1
SCHEMBL12700908 0.76 TAAR1 (0.46) ALDH1A1MAPTL3MBTL1HRH3TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103254331-B Process for producing functionalized polymers BRIDGESTONE CORP 2015-01-21 CN claimed
CN-101367892-B Method for preparing functionalized polymers BRIDGESTONE CORP 2014-01-29 CN claimed
CN-103254331-A Process for producing functionalized polymers BRIDGESTONE CORP 2013-08-21 CN claimed
CN-101367892-A Method for preparing functionalized polymers BRIDGESTONE CORP (JP) 2009-02-18 CN claimed
CN-103254331-B Process for producing functionalized polymers BRIDGESTONE CORP 2015-01-21 CN disclosed
CN-101367892-B Method for preparing functionalized polymers BRIDGESTONE CORP 2014-01-29 CN disclosed
CN-103254331-A Process for producing functionalized polymers BRIDGESTONE CORP 2013-08-21 CN disclosed
CN-101367892-A Method for preparing functionalized polymers BRIDGESTONE CORP (JP) 2009-02-18 CN disclosed
EP-0944638-B1 CIS-BRIDGED METAL COMPLEXES BASF AG (DE) 2003-06-11 EP disclosed
EP-0944638-A1 CIS-BRIDGED METAL COMPLEXES BASF AKTIENGESELLSCHAFT (DE) 1999-09-29 EP disclosed
WO-1998025939-A1 CIS-BRIDGED METAL COMPLEXES BASF AKTIENGESELLSCHAFT (DE) 1998-06-18 WO disclosed