Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | BLK | P51451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066943 | 1.00 | MAPT (0.39) | MAPTALDH1A1NR1I2AHRAURKA | |
| SCHEMBL7073980 | 0.78 | MAPT (0.44) | MAPTALDH1A1NR1I2AHRHPGD | |
| SCHEMBL7073978 | 0.78 | MAPT (0.44) | MAPTALDH1A1NR1I2AHRHPGD | |
| SCHEMBL7067471 | 0.72 | NPC1 (0.48) | MAPTALDH1A1NR1I2AHRKDR | |
| SCHEMBL7067474 | 0.72 | NPC1 (0.48) | MAPTALDH1A1NR1I2AHRKDR | |
| SCHEMBL7071012 | 0.71 | CYP2A6 (0.40) | MAPTALDH1A1NR1I2AHRCDK5 | |
| SCHEMBL7071008 | 0.71 | CYP2A6 (0.40) | MAPTALDH1A1NR1I2AHRCDK5 | |
| SCHEMBL7074094 | 0.71 | PIP4K2A (0.43) | MAPTALDH1A1NR1I2AHRPIM1 | |
| SCHEMBL2131974 | 0.70 | MEN1 (0.72) | MAPTALDH1A1AURKADAPK3LCK | |
| SCHEMBL2131978 | 0.70 | MEN1 (0.72) | MAPTALDH1A1AURKADAPK3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-07-17 | — | — | US | disclosed |
| WO-2003053976-A1 | PIPAZOLO [1,5-a] PYRIMIDINE DERIVATIVES AS MODULATORS OF PPAR | BIOVITRUM AB (SE) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134862-A1 | Compounds | PPARG, PPARA, PPARD | MAPT 4576/4885ALDH1A1 946/4885NR1I2 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.