Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 10/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071008 | 1.00 | CYP2A6 (0.40) | CYP2A6DDX3XALDH1A1NR1I2AHR | |
| SCHEMBL7073980 | 0.79 | MAPT (0.44) | DDX3XALDH1A1NR1I2AHRMAPT | |
| SCHEMBL7073978 | 0.79 | MAPT (0.44) | DDX3XALDH1A1NR1I2AHRMAPT | |
| SCHEMBL7074094 | 0.77 | PIP4K2A (0.43) | ALDH1A1NR1I2AHRMAPTHPGD | |
| SCHEMBL15756546 | 0.74 | RAB9A (0.57) | DDX3XALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7066942 | 0.71 | MAPT (0.39) | ALDH1A1NR1I2AHRMAPTHPGD | |
| SCHEMBL7067474 | 0.71 | NPC1 (0.48) | ALDH1A1NR1I2AHRMAPTHPGD | |
| SCHEMBL7066943 | 0.71 | MAPT (0.39) | ALDH1A1NR1I2AHRMAPTHPGD | |
| SCHEMBL7067471 | 0.71 | NPC1 (0.48) | ALDH1A1NR1I2AHRMAPTHPGD | |
| SCHEMBL17576043 | 0.66 | CYP2A6 (0.51) | CYP2A6ALDH1A1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-07-17 | — | — | US | disclosed |
| WO-2003053976-A1 | PIPAZOLO [1,5-a] PYRIMIDINE DERIVATIVES AS MODULATORS OF PPAR | BIOVITRUM AB (SE) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134862-A1 | Compounds | PPARG, PPARA, PPARD | CYP2A6 397/4885DDX3X 1754/4885ALDH1A1 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.