Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 13/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394803 | 0.90 | CNR1 (0.57) | DRD4CNR1CNR2 | |
| SCHEMBL4394806 | 0.90 | CNR1 (0.57) | DRD4CNR1CNR2 | |
| SCHEMBL2747078 | 0.85 | DRD4 (0.67) | DRD4KMT2ADPP4KCNH2DPP7 | |
| SCHEMBL6850062 | 0.83 | DRD4 (0.59) | DRD4KMT2ADPP4KCNH2DPP7 | |
| SCHEMBL6848680 | 0.83 | ACACB (0.57) | DRD4 | |
| SCHEMBL2751444 | 0.80 | DRD4 (0.64) | DRD4KMT2ADPP4KCNH2DPP7 | |
| SCHEMBL3456146 | 0.78 | NPC1 (0.65) | DRD4KMT2ADPP4KCNH2DPP7 | |
| SCHEMBL3954720 | 0.78 | NPC1 (0.65) | DRD4KMT2ADPP4KCNH2DPP7 | |
| SCHEMBL30073645 | 0.78 | NPC1 (0.65) | DRD4KMT2ADPP4KCNH2DPP7 | |
| SCHEMBL6712374 | 0.77 | DRD4 (0.53) | DRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | DRD4 179/4885KMT2A 588/4885DPP4 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.