Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.57 |
| ▸ | ACACA | Q13085 | 11/20 | 0.57 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13590717 | 0.91 | ACACB (0.67) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7066997 | 0.83 | DRD4 (0.59) | DRD4 | |
| SCHEMBL30182333 | 0.81 | MAPK14 (0.57) | ACACBACACAPBKCYP2C9 | |
| SCHEMBL8897974 | 0.80 | ACACB (0.58) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8897971 | 0.80 | ACACB (0.58) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2747078 | 0.79 | DRD4 (0.67) | DRD4 | |
| SCHEMBL6039406 | 0.77 | ACACB (0.69) | ACACBACACA | |
| SCHEMBL6039411 | 0.77 | ACACB (0.69) | ACACBACACA | |
| SCHEMBL6850062 | 0.77 | DRD4 (0.59) | DRD4 | |
| SCHEMBL18534331 | 0.76 | EPHX1 (0.52) | ACACBACACAPBK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242609-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-12-02 | — | — | US | disclosed |
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | ACACB 4699/4885ACACA 3917/4885PBK 4552/4885 |
| US-20040242609-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | MCHR1, MCHR2, MC4R | ACACB 4215/4885ACACA 2767/4885PBK 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.