Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068092 | 0.91 | OPRM1 (0.42) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL6236413 | 0.87 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL6234263 | 0.87 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL2770397 | 0.87 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL7067220 | 0.86 | KDM4E (0.54) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL7065791 | 0.85 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL7066810 | 0.84 | CHRM2 (0.41) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL5685787 | 0.84 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL5685782 | 0.84 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL7107188 | 0.84 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |