SCHEMBL7067347

SCHEMBL7067347

COc1ccc(N=Nc2ccc(N)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.73
MAPK1 P28482 3/20 0.73
ALDH1A1 P00352 2/20 0.70
CYP3A4 P08684 1/20 0.70
MAPT P10636 8/20 0.64
RAB9A P51151 7/20 0.64
NPC1 O15118 5/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
PTGS2 P35354 1/20 0.58
APP P05067 2/20 0.57
NR4A1 P22736 1/20 0.57
KDM4E B2RXH2 2/20 0.56
LMNA P02545 1/20 0.56
GAA P10253 1/20 0.54
GFER P55789 1/20 0.54
PKM P14618 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11153232 1.00 TDP1 (0.73) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL14845759 1.00 TDP1 (0.73) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL1405603 0.88 CA1 (0.65) TDP1MAPK1MAPTRAB9ANPC1
SCHEMBL1405602 0.88 CA1 (0.65) TDP1MAPK1MAPTRAB9ANPC1
Anisole SCHEMBL10608079 0.88 MAPT (0.69) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL5097 0.85
SCHEMBL8526630 0.85 TDP1 (1.00) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL5601373 0.83 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL357435 0.83 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4MAPT
SCHEMBL21840887 0.83 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013718-B1 Disazo dye for thermal transfer recording, and thermal transfer sheet and ink for thermal transfer recording, employing it MITSUBISHI CHEM CORP (JP) 2003-06-04 EP disclosed
US-6309807-B1 CONTAINING BINDER MITSUBISHI CHEMICAL CORPORATION (JP) 2001-10-30 US disclosed
EP-1013718-A1 Disazo dye for thermal transfer recording, and thermal transfer sheet and ink for thermal transfer recording, employing it MITSUBISHI CHEMICAL CORPORATION (JP) 2000-06-28 EP disclosed
EP-0482508-B1 Biscationic azo dyes and their intermediates BASF AG (DE) 1995-07-12 EP disclosed
EP-0482508-A1 Biscationic azo dyes and their intermediates BASF Aktiengesellschaft (DE) 1992-04-29 EP disclosed
EP-0177978-A2 Naphthol amine derivatives BAYER AG (DE) 1986-04-16 EP disclosed
EP-0097289-A2 Azo dyestuffs BAYER AG (DE) 1984-01-04 EP disclosed
US-4396545-A Bis(arylazo)diimides pigments GULF OIL CORPORATION (US) 1983-08-02 US disclosed
US-4236007-A YELLOW SHADES ON POLYESTERS CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-25 US disclosed
US-4208324-A Disperse diaminopyridine-3-azo dyestuffs CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4014864-A POLYESTER FIBERS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-3988312-A TETRAKISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3987026-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1976-10-19 US disclosed
US-3971771-A DYES FOR POLYESTERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3964862-A Process for dyeing and printing textile materials of synthetic organic fibers CIBA-GEIGY AG (CH) 1976-06-22 US disclosed
US-3954398-A Polyester fibers dyed with a disazo disperse dyestuff CIBA-GEIGY AG (CH) 1976-05-04 US disclosed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3933786-A Heterocyclic-azo-phenyl compounds containing a styrl group CIBA-GEIGY AG (CH) 1976-01-20 US disclosed