Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.94 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.89 |
| ▸ | APP | P05067 | 2/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526630 | 0.97 | TDP1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5097 | 0.97 | — | — | |
| Ethane SCHEMBL11031442 | 0.94 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL3947579 | 0.94 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL1827219 | 0.94 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL357435 | 0.94 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5601373 | 0.94 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Methane SCHEMBL22289589 | 0.94 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL208637 | 0.94 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL4376059 | 0.94 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891408-B2 | Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane | SOOCHOW UNIVERSITY (CN) | 2024-02-06 | — | — | US | claimed |
| CN-112500428-B | Application of anilino lithium compound in catalyzing reaction of carboxylic acid compound and borane hydroboration | 苏州大学 | 2022-04-15 | — | — | CN | claimed |
| CN-109651082-B | Method for preparing aliphatic alcohol at room temperature | 苏州大学 | 2021-11-09 | — | — | CN | claimed |
| US-20210221828-A1 | APPLICATION OF LITHIUM 4-METHOXYANILINE IN CATALYSIS OF HYDROBORATION REACTION OF IMINE AND BORANE | SOOCHOW UNIVERSITY (CN) | 2021-07-22 | — | — | US | claimed |
| CN-112500428-A | Application of anilino lithium compound in catalyzing reaction of carboxylic acid compound and borane hydroboration | 苏州大学 | 2021-03-16 | — | — | CN | claimed |
| CN-109503641-B | Method for preparing borate ester based on anilino lithium compound | 苏州大学 | 2021-01-01 | — | — | CN | claimed |
| CN-109369696-B | Method for preparing alcohol compound by using anilino lithium compound as catalyst | 苏州大学 | 2021-01-01 | — | — | CN | claimed |
| CN-109485668-B | Method for preparing boric acid ester at room temperature | 苏州大学 | 2020-08-14 | — | — | CN | claimed |
| WO-2020118922-A1 | METHOD FOR PREPARING BORIC ACID ESTER BASED ON LITHIUM COMPOUND | 苏州大学 | 2020-06-18 | — | — | WO | claimed |
| CN-109289913-B | Application of 4-methoxyanilino lithium in catalysis of imine and borane hydroboration reaction | 苏州大学张家港工业技术研究院 | 2020-04-17 | — | — | CN | claimed |
| US-11891408-B2 | Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane | SOOCHOW UNIVERSITY (CN) | 2024-02-06 | — | — | US | disclosed |
| US-11891408-B2 | Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane | SOOCHOW UNIVERSITY (CN) | 2024-02-06 | — | — | US | disclosed |
| US-11891408-B2 | Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane | SOOCHOW UNIVERSITY (CN) | 2024-02-06 | — | — | US | disclosed |
| US-11845068-B2 | Use of n-butyllithium for catalyzing hydroboration of imine and borane | SOOCHOW UNIVERSITY (CN) | 2023-12-19 | — | — | US | disclosed |
| US-11680075-B2 | Application of 4-MePhNHLi in catalyzing hydroboration reaction of imine and borane | SOOCHOW UNIVERSITY (CN) | 2023-06-20 | — | — | US | disclosed |
| CN-109289913-B | Application of 4-methoxyanilino lithium in catalysis of imine and borane hydroboration reaction | 苏州大学张家港工业技术研究院 | 2020-04-17 | — | — | CN | disclosed |
| CN-109289913-B | Application of 4-methoxyanilino lithium in catalysis of imine and borane hydroboration reaction | 苏州大学张家港工业技术研究院 | 2020-04-17 | — | — | CN | disclosed |
| CN-109289913-B | Application of 4-methoxyanilino lithium in catalysis of imine and borane hydroboration reaction | 苏州大学张家港工业技术研究院 | 2020-04-17 | — | — | CN | disclosed |
| WO-2020073179-A1 | APPLICATION OF LITHIUM 4-METHOXYANILINE IN CATALYSIS OF HYDROBORATION REACTION OF IMINE AND BORANE | 南通纺织丝绸产业技术研究院 | 2020-04-16 | — | — | WO | disclosed |
| WO-2020073179-A1 | APPLICATION OF LITHIUM 4-METHOXYANILINE IN CATALYSIS OF HYDROBORATION REACTION OF IMINE AND BORANE | 南通纺织丝绸产业技术研究院 | 2020-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11680075-B2 | Application of 4-MePhNHLi in catalyzing hydroboration reaction of imine and borane | HRH4, HRH3, HRH1 | TDP1 4322/4885MAPK1 2783/4885ALDH1A1 2372/4885 |
| US-11845068-B2 | Use of n-butyllithium for catalyzing hydroboration of imine and borane | INMT, SLC6A12, ICMT | TDP1 3005/4885MAPK1 2897/4885ALDH1A1 4186/4885 |
| US-20210221828-A1 | APPLICATION OF LITHIUM 4-METHOXYANILINE IN CATALYSIS OF HYDROBORATION REACTION OF IMINE AND BORANE | ME1, MCM4, INMT | TDP1 3311/4885MAPK1 1247/4885ALDH1A1 3287/4885 |
| US-11891408-B2 | Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane | ME1, MCM4, INMT | TDP1 3311/4885MAPK1 1247/4885ALDH1A1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.