Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065655 | 0.82 | — | — | |
| SCHEMBL8571684 | 0.78 | CES1 (0.47) | TSHRCYP3A4CES1SMN1; SMN2HPGD | |
| SCHEMBL7069777 | 0.78 | — | — | |
| SCHEMBL7065880 | 0.75 | — | — | |
| Carbon Tetrachloride SCHEMBL28852525 | 0.75 | TSHR (0.57) | TSHRCYP3A4CES1SMN1; SMN2HPGD | |
| SCHEMBL27826133 | 0.74 | TSHR (0.41) | TSHRCYP3A4CES1SMN1; SMN2HPGD | |
| SCHEMBL15863093 | 0.73 | TSHR (0.39) | TSHRCYP3A4CES1SMN1; SMN2HPGD | |
| SCHEMBL29300111 | 0.73 | CES1 (0.47) | TSHRCYP3A4CES1SMN1; SMN2HPGD | |
| SCHEMBL278799 | 0.72 | TSHR (0.48) | TSHRCYP3A4CES1SMN1; SMN2HPGD | |
| SCHEMBL25588711 | 0.71 | TSHR (0.42) | TSHRCYP3A4CES1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891988-B1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0451645-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0891988-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| CN-1019580-B | Components and catalysts for the polymerization of olefins | HIMONT INC (US) | 1992-12-23 | — | — | CN | disclosed |
| US-5068213-A | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | HINMONT INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| CN-1055933-A | Components and catalysts for the polymerization of olefins | HIMONT INC (US) | 1991-11-06 | — | — | CN | disclosed |
| EP-0451645-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-10-16 | — | — | EP | disclosed |