Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 15/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827014 | 0.82 | EGFR (0.62) | EGFRERBB2GAK | |
| SCHEMBL6641709 | 0.81 | EGFR (0.54) | EGFRERBB2GAK | |
| SCHEMBL6258057 | 0.80 | EGFR (0.51) | EGFRERBB2GAK | |
| SCHEMBL6644237 | 0.80 | EGFR (0.49) | EGFRERBB2GAK | |
| SCHEMBL7169626 | 0.79 | EGFR (0.43) | EGFRERBB2GAK | |
| SCHEMBL6685298 | 0.79 | EGFR (0.49) | EGFRERBB2GAK | |
| SCHEMBL6637307 | 0.78 | EGFR (0.51) | EGFRERBB2GAK | |
| Hydrochloric Acid SCHEMBL6254830 | 0.77 | EGFR (0.60) | EGFRERBB2GAK | |
| SCHEMBL6266068 | 0.76 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL6256954 | 0.75 | EGFR (0.55) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | claimed |