Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.51 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | SOD1 | P00441 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | HTR1D | P28221 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306056 | 0.87 | MEN1 (0.56) | MEN1KMT2ASOD1ALDH1A1HTR1A | |
| SCHEMBL14103827 | 0.87 | KMT2A (0.58) | MEN1KMT2ASOD1ALDH1A1HTR1A | |
| SCHEMBL5787289 | 0.86 | MAPT (0.59) | MEN1KMT2ASOD1ALDH1A1HTT | |
| SCHEMBL5787020 | 0.86 | MEN1 (0.54) | MEN1KMT2ASOD1ALDH1A1HTR1A | |
| SCHEMBL3128886 | 0.84 | CHRNA7 (0.58) | MEN1KMT2ACHRNA7CHRNA10CHRNA9 | |
| SCHEMBL27937113 | 0.83 | HTR1A (0.48) | MEN1KMT2ACHRNA7CHRNA10CHRNA9 | |
| SCHEMBL3233096 | 0.82 | MEN1 (0.53) | MEN1KMT2ACHRNA7CHRNA10CHRNA9 | |
| SCHEMBL4499479 | 0.81 | SYK (0.67) | SYK | |
| SCHEMBL1812286 | 0.80 | MAPT (0.62) | MEN1KMT2ASYKALDH1A1HTT | |
| SCHEMBL6151540 | 0.80 | MAPT (0.62) | MEN1KMT2ASYKALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |