Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.47 |
| ▸ | F10 | P00742 | 6/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066510 | 0.83 | PRSS1 (0.49) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7064662 | 0.81 | ITGB3 (0.48) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7068120 | 0.77 | GRM2 (0.51) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8152970 | 0.76 | ITGB3 (0.49) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8137355 | 0.76 | ITGB3 (0.49) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7068806 | 0.75 | GRM2 (0.48) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7069257 | 0.74 | GRM2 (0.61) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8147135 | 0.74 | ITGB3 (0.49) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL8146587 | 0.74 | ITGB3 (0.49) | ITGB3PRSS1PRSS2ITGA2BPRSS3 | |
| SCHEMBL7386950 | 0.74 | GRM2 (0.63) | ITGB3PRSS1PRSS2ITGA2BPRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |