Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572887 | 0.94 | HSD17B10 (0.41) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| SCHEMBL7722134 | 0.94 | HSD17B10 (0.41) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| SCHEMBL7571534 | 0.94 | HSD17B10 (0.41) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| SCHEMBL6843066 | 0.94 | HSD17B10 (0.49) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| Water SCHEMBL5058850 | 0.91 | HSD17B10 (0.47) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| SCHEMBL8958670 | 0.89 | HSD17B10 (0.41) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| SCHEMBL8958264 | 0.89 | HSD17B10 (0.44) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| SCHEMBL8958676 | 0.88 | HSD17B10 (0.40) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL5153564 | 0.87 | HSD17B10 (0.43) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 | |
| SCHEMBL8958281 | 0.87 | HSD17B10 (0.43) | HSD17B10KDM4ETSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124443-B2 | Organic diodes and materials | MARROCCO MATTHEW L (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100112751-A1 | ORGANIC DIODES AND MATERIALS | MARROCCO III MATTHEW L | 2010-05-06 | — | — | US | disclosed |
| US-7655961-B2 | Organic diodes and materials | MAXDEM INCORPORATED (US) | 2010-02-02 | — | — | US | disclosed |
| WO-2005034199-A2 | ORGANIC DIODES AND MATERIALS | MAXDEM INCORPORATED (US) | 2005-04-14 | — | — | WO | disclosed |
| US-20050072971-A1 | Organic diodes and materials | IPCO LLC | 2005-04-07 | — | — | US | disclosed |