SCHEMBL7067654

SCHEMBL7067654

C=CC(=O)OCCCC(N)=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.68
ALDH1A1 P00352 6/20 0.68
CYP3A4 P08684 3/20 0.68
HPGD P15428 1/20 0.61
TP53 P04637 4/20 0.56
HIF1A Q16665 3/20 0.56
HSD17B10 Q99714 1/20 0.56
THRB P10828 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MAPK1 P28482 1/20 0.41
ATM Q13315 1/20 0.39
MAPT P10636 2/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
FGFR4 P22455 1/20 0.36
HCAR2 Q8TDS4 3/20 0.34
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
POLB P06746 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8668389 0.94 TSHR (0.72) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8156816 0.92 TSHR (0.76) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7069294 0.89 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16405350 0.84 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2778187 0.84 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL244114 0.84 TSHR (0.95) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL321925 0.84 TSHR (0.85) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL4873976 0.83 TSHR (0.75) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2872702 0.83 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1433903 0.83 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113006376-B Supporting steel pipe column for deep foundation pit reverse construction method and machining process thereof 中厦建设有限公司 2022-05-03 CN claimed
CN-109791353-B Photosensitive resin composition and photosensitive resin printing plate precursor comprising same 东丽株式会社 2022-07-12 CN disclosed
CN-113006376-B Supporting steel pipe column for deep foundation pit reverse construction method and machining process thereof 中厦建设有限公司 2022-05-03 CN disclosed
CN-1131289-C Pressure-sensitive adhesive composition and pressure-sensitive adhesive sheets NITTO DENKO CORP (JP) 2003-12-17 CN disclosed
EP-0819713-B1 Pressure-sensitive adhesive composition and pressure-sensitive adhesive sheets NITTO DENKO CORP (JP) 2003-06-04 EP disclosed
EP-0956318-A1 RADIATION-CURABLE COMPOSITION DSM N.V. (NL) 1999-11-17 EP disclosed
US-5852119-A Pressure-sensitive adhesive composition and pressure-sensitive adhesive sheets NITTO DENKO CORPORATION (JP) 1998-12-22 US disclosed
EP-0704509-B1 Pressure-sensitive adhesive composition and pressure-sensitive adhesive sheets using the composition NITTO DENKO CORP (JP) 1998-12-16 EP disclosed
WO-1998033855-A1 RADIATION-CURABLE COMPOSITION DSM N.V. (NL) 1998-08-06 WO disclosed
CN-1174224-A Pressure-sensitive adhesive composition and pressure-sensitive adhesive sheets NITTO DENKO CORP (JP) 1998-02-25 CN disclosed
EP-0819713-A1 Pressure-sensitive adhesive composition and pressure-sensitive adhesive sheets NITTO DENKO CORPORATION (JP) 1998-01-21 EP disclosed
US-5604035-A COPOLYMER OF (METH)ACRYLIC ACID ALKYL ESTER AND (METH)ACRYLIC ALKYL ESTER HAVING CARBOXYL GROUP OR HYDROXYL GROUP AT TERMINAL END OF SIDE CHAIN NITTO DENKO CORPORATION (JP) 1997-02-18 US disclosed
EP-0704509-A1 Pressure-sensitive adhesive composition and pressure-sensitive adhesive sheets using the composition NITTO DENKO CORPORATION (JP) 1996-04-03 EP disclosed