Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.84 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | DRD4 | P21917 | 4/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497509 | 0.94 | OPRM1 (0.82) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL6507423 | 0.93 | OPRM1 (0.75) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL6503296 | 0.90 | OPRM1 (0.73) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL6504180 | 0.90 | OPRM1 (0.76) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL6506818 | 0.89 | OPRM1 (0.72) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL6507053 | 0.89 | OPRM1 (0.72) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL6504792 | 0.89 | OPRM1 (0.72) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL6498522 | 0.89 | OPRM1 (0.74) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL7067624 | 0.89 | OPRM1 (0.74) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL6507448 | 0.88 | OPRM1 (0.71) | OPRM1OPRK1OPRL1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |