Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708027 | 0.90 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL13374875 | 0.90 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL25721685 | 0.90 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL17337592 | 0.90 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL17337593 | 0.90 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL18289855 | 0.90 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL14962705 | 0.90 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL21708028 | 0.90 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL18811712 | 0.83 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL18522915 | 0.82 | CYP2D6 (0.32) | CYP2D6DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920325-A3 | TETRAPEPTIDE DERIVATIVES OF DOLASTATIN AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-04 | — | — | EP | disclosed |
| EP-0920325-A2 | TETRAPEPTIDE DERIVATIVES OF DOLASTATIN AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998004278-A2 | TETRAPEPTIDE DERIVATIVES OF DOLASTATIN AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-05 | — | — | WO | disclosed |