SCHEMBL7069013

SCHEMBL7069013

CCCCc1ncc2ccccc2n1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 7/20 0.49
TLR7 Q9NYK1 1/20 0.41
PDE4A P27815 4/20 0.41
PDE4B Q07343 4/20 0.41
PDE4C Q08493 4/20 0.41
PDE4D Q08499 4/20 0.41
PDE3B Q13370 2/20 0.41
PDE3A Q14432 2/20 0.41
PARP1 P09874 1/20 0.40
TRPV1 Q8NER1 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30336491 0.95 TLR8 (0.50) TLR8TLR7TRPV1
SCHEMBL4557233 0.95 TLR8 (0.50) TLR8TLR7TRPV1
SCHEMBL27991341 0.93 TLR8 (0.49) TLR8TLR7TRPV1
SCHEMBL9971271 0.89 KDM4E (0.44) TLR8TRPV1KDM4EALDH1A1HPGD
SCHEMBL28146413 0.85 GPBAR1 (0.49) TLR8ALDH1A1HPGDSMN1; SMN2
SCHEMBL28206532 0.85 TLR8 (0.43) TLR8PDE4APDE4BPDE4CPDE4D
SCHEMBL7074398 0.82 KDM4E (0.37) KDM4EALDH1A1MAPTHPGD
SCHEMBL8501798 0.82 KDM4E (0.37) TLR8KDM4EALDH1A1MAPTHPGD
SCHEMBL7548524 0.82 KDM4E (0.37) TLR8KDM4EALDH1A1MAPTHPGD
SCHEMBL28119918 0.81 TSHR (0.41) TLR8KDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
CN-102971305-B Heterocyclic antiviral compounds F. HOFFMANN-LA ROCHE AG (CH) 2016-02-03 CN disclosed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP disclosed
CN-1050617-C Latent catalysts, cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 2000-03-22 CN disclosed
CN-1050618-C Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 2000-03-22 CN disclosed
CN-1035823-C Process for preparing latent catalysts for curing epoxy resins DOW CHEMICAL CO (US) 1997-09-10 CN disclosed
EP-0328020-B1 Use of a catalyst in epoxy compositions DOW CHEMICAL CO (US) 1996-10-09 EP disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
CN-1118793-A Latent catalysts, cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 1996-03-20 CN disclosed
CN-1118794-A Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 1996-03-20 CN disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
CN-1056699-A Latent catalysts and cure-inhibited epoxy resin compositions and laminates made therefrom DOW CHEMICAL CO (US) 1991-12-04 CN disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed