Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701885 | 0.78 | FFAR4 (0.46) | FFAR4CYP3A4CYP2C9APPF10 | |
| SCHEMBL6700407 | 0.78 | FFAR4 (0.50) | FFAR4CYP3A4CYP2C9APPF10 | |
| SCHEMBL6697870 | 0.77 | FFAR4 (0.47) | FFAR4CYP3A4CYP2C9APPF10 | |
| SCHEMBL6699132 | 0.76 | FFAR4 (0.44) | FFAR4CYP3A4CYP2C9APPF10 | |
| SCHEMBL6703184 | 0.73 | FFAR4 (0.46) | FFAR4CYP3A4CYP2C9APPF10 | |
| SCHEMBL19478713 | 0.69 | HRH3 (0.46) | FFAR4CYP3A4CYP2C9APPF10 | |
| SCHEMBL9501457 | 0.69 | CYP3A4 (0.60) | FFAR4CYP3A4CYP2C9APP | |
| SCHEMBL21417736 | 0.68 | CYP3A4 (0.54) | FFAR4CYP3A4CYP2C9APP | |
| SCHEMBL19097887 | 0.68 | CYP3A4 (0.38) | FFAR4CYP3A4CYP2C9APPFEN1 | |
| SCHEMBL2889244 | 0.68 | FFAR4 (0.46) | FFAR4HRH3SLC6A4HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368300-A1 | SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070462-A1 | SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |