Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | APP | P05067 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19992988 | 0.91 | CYP3A4 (0.53) | CYP3A4APPCYP2C9HSP90AA1GAA | |
| SCHEMBL18855003 | 0.91 | CYP3A4 (0.53) | CYP3A4APPCYP2C9HSP90AA1GAA | |
| SCHEMBL21387527 | 0.91 | CYP3A4 (0.53) | CYP3A4APPCYP2C9HSP90AA1GAA | |
| SCHEMBL18807493 | 0.91 | CYP3A4 (0.53) | CYP3A4APPCYP2C9HSP90AA1GAA | |
| SCHEMBL18458595 | 0.91 | CYP3A4 (0.56) | CYP3A4APPCYP2C9HSP90AA1GAA | |
| SCHEMBL10091195 | 0.91 | CYP3A4 (0.56) | CYP3A4APPCYP2C9HSP90AA1GAA | |
| SCHEMBL14211884 | 0.91 | CYP3A4 (0.56) | CYP3A4APPCYP2C9HSP90AA1GAA | |
| SCHEMBL13083626 | 0.90 | CYP3A4 (0.55) | CYP3A4APPCYP2C9HSP90AA1GAA | |
| SCHEMBL18808206 | 0.90 | CYP3A4 (0.54) | CYP3A4APPCYP2C9MAPTKMT2A | |
| SCHEMBL18411541 | 0.88 | CYP3A4 (0.50) | CYP3A4APPCYP2C9HSP90AA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924447-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2024-01-24 | — | — | EP | disclosed |
| US-20230357637-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-09 | — | — | US | disclosed |
| EP-4273207-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2023-11-08 | — | — | EP | disclosed |
| EP-4261267-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2023-10-18 | — | — | EP | disclosed |
| EP-4261268-A1 | LIQUID CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2023-10-18 | — | — | EP | disclosed |
| US-20230323209-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| EP-3755764-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2023-05-10 | — | — | EP | disclosed |
| EP-3802730-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-04-19 | — | — | EP | disclosed |
| US-11312909-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2022-04-26 | — | — | US | disclosed |
| EP-2781578-B1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-9580654-B2 | Liquid crystal composition and liquid crystal display device using the same | DIC CORPORATION (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20170029700-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DIC CORPORATION (JP) | 2017-02-02 | — | — | US | disclosed |
| EP-3121247-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2017-01-25 | — | — | EP | disclosed |
| US-20170015906-A1 | LIQUID CRYSTAL COMPOSITION | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) | 2017-01-19 | — | — | US | disclosed |
| EP-0338059-B1 | IMPROVED LIQUID CRYSTAL MIXTURE | CASIO COMPUTER COMPANY LIMITED (JP) | 1993-04-21 | — | — | EP | disclosed |
| EP-0354940-A1 | IMPROVED LIQUID CRYSTAL MIXTURE | MERCK PATENT GmbH (DE) | 1990-02-21 | — | — | EP | disclosed |
| EP-0338059-A1 | IMPROVED LIQUID CRYSTAL MIXTURE | CASIO COMPUTER COMPANY LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |
| WO-1989006677-A1 | IMPROVED LIQUID CRYSTAL MIXTURE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-07-27 | — | — | WO | disclosed |
| WO-1989003867-A1 | IMPROVED LIQUID CRYSTAL MIXTURE | CASIO COMPUTER COMPANY LIMITED (JP) | 1989-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | CYP3A4 1699/4885APP 1164/4885CYP2C9 1741/4885 |
| US-11312909-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, LCP1, MAP1LC3C | CYP3A4 2561/4885APP 1645/4885CYP2C9 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.