Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807637 | 0.78 | AKT1 (0.51) | ADORA1MAPK14EGFRRAF1ADORA3 | |
| SCHEMBL14502354 | 0.77 | AKT1 (0.65) | ADORA1MAPK14EGFRRAF1ADORA3 | |
| SCHEMBL8809320 | 0.75 | AKT1 (0.54) | ADORA1MAPK14EGFRRAF1ADORA3 | |
| SCHEMBL8811450 | 0.75 | MAPK14 (0.57) | ADORA1MAPK14EGFRRAF1ADORA3 | |
| SCHEMBL14502340 | 0.74 | AKT1 (0.60) | ADORA1MAPK14EGFRRAF1ADORA3 | |
| SCHEMBL5673928 | 0.74 | MAPK14 (0.40) | ADORA1MAPK14EGFRRAF1ADORA3 | |
| SCHEMBL14592998 | 0.74 | IGF1R (0.45) | ADORA1MAPK14EGFRRAF1ADORA3 | |
| SCHEMBL5700356 | 0.73 | RORC (0.53) | GSK3BPTGS2PTGS1 | |
| SCHEMBL8810466 | 0.73 | MAPK14 (0.78) | ADORA1MAPK14EGFRRAF1ADORA3 | |
| SCHEMBL5760781 | 0.73 | MAPK14 (0.55) | ADORA1MAPK14EGFRRAF1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045950-A1 | PYRAZOLOPYRIDINE DERIVTIVES AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |