Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | WDR5 | P61964 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | FASN | P49327 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27530062 | 0.95 | POLB (0.66) | HPGDMAPK1POLBSLC6A7MEN1 | |
| SCHEMBL7074519 | 0.88 | KDM4E (0.61) | MAPK1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10721898 | 0.88 | MAPK1 (0.85) | HPGDMAPK1POLBSLC6A7MEN1 | |
| SCHEMBL7071445 | 0.87 | F10 (0.62) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL9189037 | 0.84 | ITGB3 (0.54) | HPGDMAPK1POLBSLC6A7MEN1 | |
| SCHEMBL4719812 | 0.83 | MAPK1 (0.77) | HPGDMAPK1POLBSLC6A7MEN1 | |
| Hydrochloric Acid SCHEMBL8519571 | 0.83 | ITGB3 (0.53) | HPGDMAPK1POLBSLC6A7MEN1 | |
| SCHEMBL24065200 | 0.81 | HPGD (0.70) | HPGDMAPK1MEN1KMT2ATSHR | |
| SCHEMBL6614562 | 0.81 | HPGD (1.00) | HPGDMAPK1POLBSLC6A7MEN1 | |
| Hydrochloric Acid SCHEMBL8718465 | 0.81 | ITGB3 (0.68) | HPGDPOLBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |