Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GOT1 | P17174 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31738482 | 1.00 | CYP19A1 (0.61) | CYP19A1CYP3A4NPSR1LMNACYP1A2 | |
| Azetidine SCHEMBL28099548 | 0.91 | CYP19A1 (0.53) | CYP19A1CYP3A4NPSR1LMNACYP1A2 | |
| SCHEMBL871138 | 0.88 | CYP19A1 (0.53) | CYP19A1CYP3A4NPSR1LMNACYP1A2 | |
| SCHEMBL29481851 | 0.88 | CYP19A1 (0.53) | CYP19A1CYP3A4NPSR1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL6061889 | 0.86 | CYP19A1 (0.52) | CYP19A1CYP3A4NPSR1LMNACYP1A2 | |
| SCHEMBL9807642 | 0.85 | CYP19A1 (0.54) | CYP19A1CYP3A4LMNACYP1A2CYP2C9 | |
| SCHEMBL28873268 | 0.82 | CYP19A1 (0.62) | CYP19A1CYP3A4LMNACYP1A2SMN1; SMN2 | |
| Succinic Acid SCHEMBL21385162 | 0.81 | KDR (0.53) | CYP19A1ALDH1A1MAPT | |
| SCHEMBL28173505 | 0.78 | SCN9A (0.54) | CYP19A1CYP3A4NPSR1LMNACYP1A2 | |
| SCHEMBL291353 | 0.77 | KDM4E (0.47) | CYP19A1CYP3A4LMNACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985320-B | Benzyl phthalazine compound and its preparation method and application | 复旦大学 | 2018-10-26 | — | — | CN | claimed |
| CN-105985320-A | Benzylphthalazine compound and its preparation method and use | 复旦大学 | 2016-10-05 | — | — | CN | claimed |
| CN-1496362-A | Non-imidazole compounds as histamine H3 antagonists | ���鹫˾ | 2004-05-12 | — | — | CN | claimed |
| CN-1469873-A | Piperidine compounds useful as antiallergic agents | ���鹫˾ | 2004-01-21 | — | — | CN | claimed |
| CN-1094615-A | The compositions and the method for improved analgesic effect are provided | PROCTER & GAMBLE (US) | 1994-11-09 | — | — | CN | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| CN-117362661-A | Hyperbranched carbon-nitrogen heterocyclic resin and resin composition, prepreg, circuit substrate and printed circuit board thereof | 浙江华正新材料股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| US-11850234-B2 | Enhancement of cancer treatment efficiency via the sphingosine-1-phosphate pathway | AC BIOSCIENCE (CH) | 2023-12-26 | — | — | US | disclosed |
| EP-3668506-B1 | ENHANCEMENT OF CANCER TREATMENT EFFICIENCY VIA THE SPHINGOSINE-1-PHOSPHATE PATHWAY | AC BIOSCIENCE (CH) | 2023-12-06 | — | — | EP | disclosed |
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-107428708-B | Benzoxazine low temperature curable compositions | 亨斯迈先进材料美国有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| US-20200261420-A1 | ENHANCEMENT OF CANCER TREATMENT EFFICIENCY VIA THE SPHINGOSINE-1-PHOSPHATE PATHWAY | AC BIOSCIENCE (CH) | 2020-08-20 | — | — | US | disclosed |
| CN-111432815-A | Enhancing cancer treatment efficacy via sphingosine-1-phosphate pathway | AC生物科学公司 | 2020-07-17 | — | — | CN | disclosed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5134239-A | Quaterinary indolizine compound | THE DOW CHEMICAL COMPANY (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| CN-1055180-A | 3 of thiazolinone, azoles quinoline ketone and the imidazolone type that 2-replaces, the preparation method of 5-di-tert-butyl-hydroxy phenyl methylene derivatives | WARNER LAMBERT CO (US) | 1991-10-09 | — | — | CN | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
| CN-86107627-A | The preparation method of novel 4-benzyl-1-(2H)-phthalazinone derivatives | — | 1987-07-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11850234-B2 | Enhancement of cancer treatment efficiency via the sphingosine-1-phosphate pathway | SPHK1, S1PR1, S1PR2 | CYP19A1 3285/4885CYP3A4 4383/4885NPSR1 2289/4885 |
| US-20200261420-A1 | ENHANCEMENT OF CANCER TREATMENT EFFICIENCY VIA THE SPHINGOSINE-1-PHOSPHATE PATHWAY | SPHK1, S1PR1, S1PR2 | CYP19A1 3285/4885CYP3A4 4383/4885NPSR1 2289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.