Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.32 |
| ▸ | PPARD | Q03181 | 7/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081457 | 0.99 | ESR1 (0.38) | ESR1ARPPARGPPARDFFAR1 | |
| SCHEMBL5854405 | 0.94 | ESR1 (0.35) | ESR1AR | |
| SCHEMBL6938349 | 0.92 | ESR1 (0.32) | ESR1 | |
| SCHEMBL7085013 | 0.89 | ESR1 (0.33) | ESR1AR | |
| SCHEMBL7085015 | 0.89 | ESR1 (0.33) | ESR1AR | |
| SCHEMBL5855481 | 0.86 | ESR1 (0.47) | ESR1ARPPARG | |
| SCHEMBL5854406 | 0.86 | ESR1 (0.47) | ESR1ARPPARG | |
| SCHEMBL5856044 | 0.86 | ESR1 (0.47) | ESR1ARPPARG | |
| SCHEMBL5854247 | 0.86 | ESR1 (0.47) | ESR1ARPPARG | |
| SCHEMBL5854200 | 0.85 | ESR1 (0.47) | ESR1ARPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092695-A1 | Metal salts of 3-methyl-chromane or thiochromane derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092695-A1 | Metal salts of 3-methyl-chromane or thiochromane derivatives | NR5A1, SHBG, ESR1 | ESR1 3/4885AR 10/4885PPARG 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.