Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940247 | 0.89 | NPSR1 (0.68) | TP53LMNAMAPTCYP1A2NPSR1 | |
| SCHEMBL11802020 | 0.86 | MAPT (0.65) | TP53LMNAMAPTMEN1USP2 | |
| SCHEMBL11769344 | 0.84 | TP53 (0.72) | TP53LMNAMAPTMEN1USP2 | |
| SCHEMBL11783865 | 0.81 | TP53 (0.66) | TP53LMNAMAPTMEN1USP2 | |
| SCHEMBL27405126 | 0.81 | TP53 (0.69) | TP53LMNAMAPTMEN1USP2 | |
| SCHEMBL11579807 | 0.80 | TP53 (0.67) | TP53LMNAMAPTMEN1USP2 | |
| SCHEMBL11789031 | 0.80 | TP53 (0.62) | TP53LMNAMAPTMEN1USP2 | |
| SCHEMBL8301353 | 0.80 | TP53 (0.56) | TP53LMNAMAPTMEN1USP2 | |
| SCHEMBL11578043 | 0.79 | TP53 (0.66) | TP53LMNAMAPTMEN1USP2 | |
| SCHEMBL11578274 | 0.79 | TP53 (0.66) | TP53LMNAMAPTMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342719-A1 | Benzodiazepine derivatives useful as CCK-Receptor Antagonists | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |