Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810323 | 0.91 | MEN1 (0.55) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL11804705 | 0.89 | TP53 (0.52) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL11806947 | 0.89 | MAPT (0.72) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL11810202 | 0.88 | PTGDR2 (0.53) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL7069966 | 0.86 | TP53 (0.64) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL11804792 | 0.84 | TP53 (0.58) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL11769344 | 0.84 | TP53 (0.72) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL11783865 | 0.83 | TP53 (0.66) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL27405126 | 0.81 | TP53 (0.69) | MAPTMEN1KMT2AUSP2TP53 | |
| SCHEMBL11579807 | 0.80 | TP53 (0.67) | MAPTMEN1KMT2AUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933816-A | 3-(Substituted aminomethyl)-7-substituted-3,5-dihydro-as-triazino[4,3-a][1,5]benzodiazepines | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |