SCHEMBL7070119

SCHEMBL7070119

N#Cc1cc(C#N)cc(Oc2cccc(Oc3ccc(Cl)cc3)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
ALDH1A1 P00352 3/20 0.48
MAPT P10636 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MITF O75030 1/20 0.48
GAA P10253 1/20 0.48
GFER P55789 1/20 0.48
NLRP1 Q9C000 1/20 0.48
NOD2 Q9HC29 1/20 0.48
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CYP19A1 P11511 2/20 0.42
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
LMNA P02545 2/20 0.41
ADRB2 P07550 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921796 0.91 AR (0.50) ARSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL7074948 0.88 AR (0.54) ARSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL7074601 0.88 AR (0.54) ARSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL7073983 0.87 CYP19A1 (0.54) ARSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL7070749 0.87 SMN1; SMN2 (0.50) ARSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL12127662 0.86 AR (0.47) ARSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL7070717 0.85 MEN1 (0.50) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL7074385 0.85 KMO (0.54) ARSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL7069974 0.83 PDE4A (0.50) ARSMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL7072557 0.83 PDE4A (0.50) ARSMN1; SMN2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030181334-A1 Herbicidal method BAYER CROPSCIENCE LIMITED (GB) 2003-09-25 US disclosed
WO-2003051119-A1 NEW HERBICIDAL COMPOUNDS AND METHOD BAYER CROPSCIENCE LIMITED (GB) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181334-A1 Herbicidal method DDT, HAAO, CYP4X1 AR 4356/4885SMN1; SMN2 4836/4885ALDH1A1 184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.