SCHEMBL7070177

SCHEMBL7070177

CCCCC[C@@H]1C[C@H]1NC(=O)C1(CC(C(=O)O)C(C)OC)CCCC1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MME P08473 18/20 0.44
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7070166 1.00 MME (0.44) MMEALOX5
SCHEMBL7070168 0.80 MME (0.58) MME
SCHEMBL7070170 0.80 MME (0.58) MME
SCHEMBL7446889 0.79 MME (0.48) MME
SCHEMBL7446000 0.75 MME (0.56) MME
SCHEMBL7441944 0.73 MME (0.69) MME
SCHEMBL7441960 0.73 MME (0.69) MME
SCHEMBL7446884 0.73 MME (0.45) MME
SCHEMBL7446894 0.70 MME (0.34) MMEALOX5
SCHEMBL5892560 0.63 ALOX5 (0.47) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1296938-A1 CYCLOPENTYL-SUBSTITUTED GLUTARAMIDE DERIVATIVES AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE Pfizer Limited (GB) 2003-04-02 EP disclosed
WO-2002002513-A1 CYCLOPENTYL-SUBSTITUTED GLUTARAMIDE DERIVATIVES AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE PFIZER LIMITED (GB) 2002-01-10 WO disclosed