SCHEMBL7070310

SCHEMBL7070310

CC1=C(C)CC(CO/N=C/C(=O)O)=C(CO/N=C(/C)c2cccc(C(F)(F)F)c2)C1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
TBXA2R P21731 9/20 0.39
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TBXAS1 P24557 6/20 0.38
MAOB P27338 2/20 0.38
POLB P06746 1/20 0.37
CES2 O00748 1/20 0.37
S1PR1 P21453 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788397 0.90 KMT2A (0.43) PPARGPPARAKMT2AMEN1ALDH1A1
SCHEMBL7073238 0.86 PPARG (0.44) PPARGPPARAKMT2AMEN1TBXA2R
SCHEMBL7070313 0.80 PPARG (0.41) PPARGPPARAKMT2AMEN1TBXA2R
SCHEMBL7788358 0.78 MEN1 (0.41) PPARGPPARAKMT2AMEN1MAPT
SCHEMBL7788351 0.77 HIF1A (0.42) PPARGPPARAKMT2AMEN1HPGD
SCHEMBL7788357 0.77 HIF1A (0.42) PPARGPPARAKMT2AMEN1HPGD
SCHEMBL7795491 0.76 KMT2A (0.41) PPARGPPARAKMT2AMEN1NPC1
SCHEMBL7795487 0.76 KMT2A (0.41) PPARGPPARAKMT2AMEN1NPC1
SCHEMBL8611093 0.74 KMT2A (0.56) PPARGPPARAKMT2AMEN1TBXA2R
Acetic Acid SCHEMBL8194645 0.72 PPARG (0.50) PPARGPPARAKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095013-B1 PHENYL-METHOXYIMINO-ACETIC ACID DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-06-18 EP disclosed
US-20010018452-A1 Phenyl-methoxyimino-acetic acid derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2001-08-30 US disclosed
EP-1095013-A1 PHENYL-METHOXYIMINO-ACETIC ACID DERIVATIVES AS PESTICIDES Bayer Aktiengesellschaft (DE) 2001-05-02 EP disclosed
WO-2000003974-A1 PHENYL-METHOXYIMINO-ACETIC ACID DERIVATIVES AS PESTICIDES SYGENTA PARTICIPATIONS AG (CH) 2000-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010018452-A1 Phenyl-methoxyimino-acetic acid derivatives as pesticides HAO1, CYP1A1, HAO2 PPARG 1217/4885PPARA 1474/4885KMT2A 846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.