Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 15/20 | 0.84 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509148 | 0.91 | CCR8 (1.00) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL6501296 | 0.90 | CCR8 (0.86) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL7063399 | 0.89 | CCR8 (0.83) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL6505643 | 0.86 | CCR8 (0.78) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL6504810 | 0.85 | CCR8 (0.77) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL6501070 | 0.84 | CCR8 (0.86) | CCR8KCNH2FAAHMEN1KMT2A | |
| SCHEMBL6496005 | 0.82 | CCR8 (0.73) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL6500877 | 0.81 | CCR8 (0.71) | CCR8KCNH2MGLLMEN1KMT2A | |
| SCHEMBL6506653 | 0.81 | CCR8 (0.70) | CCR8KCNH2FAAH | |
| SCHEMBL7064954 | 0.80 | CCR8 (0.70) | CCR8KCNH2FAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |