Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl 3-Phenylpropanoate SCHEMBL304816 | 0.86 | TDP1 (0.75) | CYP4F2CYP4A11MAPTTDP1ALDH1A1 | |
| SCHEMBL12065155 | 0.85 | NPC1 (0.55) | CYP4F2CYP4A11MAPTTDP1NPC1 | |
| SCHEMBL8896718 | 0.85 | NPC1 (0.59) | CYP4F2CYP4A11MAPTTDP1NPC1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL7440447 | 0.85 | TDP1 (0.72) | CYP4F2CYP4A11MAPTTDP1ALDH1A1 | |
| SCHEMBL2773061 | 0.83 | CYP4F2 (0.68) | CYP4F2CYP4A11TDP1ABCB1ALOX5 | |
| SCHEMBL14028452 | 0.82 | CYP4F2 (0.66) | CYP4F2CYP4A11MAPTTDP1NPC1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL3322728 | 0.82 | CYP4F2 (0.70) | CYP4F2CYP4A11MAPTTDP1ALDH1A1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL311047 | 0.82 | TDP1 (0.68) | CYP4F2CYP4A11TDP1ABCB1L3MBTL1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL28983325 | 0.82 | TDP1 (0.68) | CYP4F2CYP4A11MAPTTDP1ALDH1A1 | |
| Ethyl 3-Phenylpropanoate SCHEMBL27762292 | 0.82 | TDP1 (0.68) | CYP4F2CYP4A11MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1179940-C | Novel 1,2-diphenyl-2-propen-1-one derivatives | ������ҩ��ʽ���� | 2004-12-15 | — | — | CN | disclosed |
| EP-1142865-B1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6395932-B1 | AMINOALKYL-1,2-DIPHENYL-2-PROPEN-1-ONE WHICH LOWER INTRAOCULAR PRESSURE BY CAUSING MORPHOLOGICAL CHANGE IN TRABECULAR MESHWORK CELLS. | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| CN-1336910-A | Novel 1,2-diphenyl-2-propen-1-one derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-02-20 | — | — | CN | disclosed |
| EP-1142865-A1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |