Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896857 | 0.91 | TDP1 (0.55) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL8896109 | 0.90 | DPP4 (0.55) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7071029 | 0.85 | CYP4F2 (0.59) | NPC1RAB9AMAPTALDH1A1LMNA | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.85 | TDP1 (0.68) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL8895649 | 0.84 | NPC1 (0.66) | NPC1RAB9AMAPTALDH1A1LMNA | |
| Methyl 3-Phenylpropanoate SCHEMBL27315471 | 0.84 | TDP1 (0.66) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| Methyl 3-Phenylpropanoate SCHEMBL1893702 | 0.84 | TDP1 (0.66) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| Methyl 3-Phenylpropanoate SCHEMBL27447160 | 0.84 | TDP1 (0.66) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL11629832 | 0.83 | SRD5A2 (0.56) | NPC1RAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7071088 | 0.82 | FFAR1 (0.69) | NPC1RAB9AMAPTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |