SCHEMBL7071196

SCHEMBL7071196

CCC1(CC)C(=O)N(C)CC(C)(C)N1OC(C)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.32
TACR1 P25103 2/20 0.32
CTSD P07339 1/20 0.32
CTSE P14091 1/20 0.32
BACE1 P56817 1/20 0.32
OPRM1 P35372 2/20 0.31
SIGMAR1 Q99720 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
CHRM1 P11229 1/20 0.31
BRD4 O60885 2/20 0.30
CREBBP Q92793 2/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7069061 0.86 OPRM1 (0.33) ELANETACR1CTSDCTSEBACE1
SCHEMBL7073839 0.85 ELANE (0.36) ELANECTSDCTSEBACE1OPRM1
SCHEMBL6884754 0.84 ELANE (0.30) ELANE
SCHEMBL7071712 0.82
SCHEMBL7071716 0.78
SCHEMBL5385910 0.78 IDH1 (0.34)
SCHEMBL7071090 0.77 OPRM1 (0.33) ELANETACR1CTSDCTSEBACE1
SCHEMBL7070810 0.76
SCHEMBL7066888 0.75 ELANE (0.30) ELANE
SCHEMBL7073820 0.75 ELANE (0.30) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664353-B2 Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-16 US disclosed
US-20030125494-A1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes NESVADBA PETER (CH) 2003-07-03 US disclosed
US-6479608-B1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes CIBA SPECIALTY CHEMICALS CORPORATION 2002-11-12 US disclosed