Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414561 | 1.00 | MAPT (0.47) | MAPTALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL1666085 | 0.85 | APP (0.63) | MAPTALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL3839249 | 0.84 | MAPT (0.59) | MAPTALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL5872097 | 0.78 | APP (0.48) | MAPTCYP1A2APPCA12CA2 | |
| SCHEMBL2747316 | 0.76 | MAPT (0.50) | MAPTALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL7061161 | 0.76 | ALDH1A1 (0.66) | MAPTALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL31301286 | 0.75 | FFAR1 (0.58) | MAPTALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL6940844 | 0.75 | FFAR1 (0.58) | MAPTALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL23639130 | 0.74 | MAPT (0.48) | MAPTALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL6742524 | 0.74 | MAPT (0.53) | MAPTALDH1A1NPC1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030017635-A1 | Low dielectric constant polyorganosilicon materials generated from polycarbosilanes | HONEYWELL INTERNATIONAL INC. | 2003-01-23 | — | — | US | disclosed |