SCHEMBL7071379

SCHEMBL7071379

O=S(=O)(O)c1cc(S(=O)(=O)O)c2cc(N=Nc3c(S(=O)(=O)O)cc4cc(S(=O)(=O)O)cc(O)c4c3O)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 1/20 0.68
▸ CYP1A2 P05177 3/20 0.64
▸ MAPK1 P28482 3/20 0.64
▸ CYP2C9 P11712 2/20 0.64
▸ DNASE1L3 Q13609 1/20 0.64
▸ PHLPP2 Q6ZVD8 2/20 0.56
▸ ENPP2 Q13822 8/20 0.53
▸ SUMO2 P61956 1/20 0.50
▸ SUMO1 P63165 1/20 0.50
▸ SENP7 Q9BQF6 1/20 0.50
▸ SENP2 Q9HC62 1/20 0.50
▸ KMT2A Q03164 2/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ CD40 P25942 1/20 0.45
▸ CD40LG P29965 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071374 1.00 PRMT1 (0.68) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL9273205 0.89 PRMT1 (0.73) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL11791675 0.89 PRMT1 (0.73) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL9273197 0.89 PRMT1 (0.73) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL2161281 0.88 PRMT1 (0.74) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL3042237 0.88 PRMT1 (0.74) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL11759436 0.87 CYP1A2 (0.70) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL5859444 0.87 CYP1A2 (0.70) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL29399950 0.86 PRMT1 (0.73) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL5351119 0.85 CYP1A2 (0.71) PRMT1CYP1A2MAPK1CYP2C9DNASE1L3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747704-B1 Immunoassay element containing a diaryl telluride compound to increase its stability ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-12-10 — — EP disclosed
EP-0903583-B1 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-11-12 — — EP disclosed
EP-0747702-B1 Method for washing immunoassay elements ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-08-20 — — EP disclosed
EP-0693552-B1 Analytical element, composition and method using modified apo-horseradish peroxidase JOHNSON & JOHNSON CLIN DIAG (US) 2003-04-02 — — EP disclosed
EP-0684473-B1 Immunoassay elements comprising polymers containing vanadium IV (V (+4)) ions JOHNSON & JOHNSON CLIN DIAG (US) 2001-11-07 — — EP disclosed
EP-0718626-B1 Calibrating and testing immunoassays to minimize interferences JOHNSON & JOHNSON CLIN DIAG (US) 2001-10-04 — — EP disclosed
EP-0699908-B1 Immunoassay elements having stable leuco dye coatings JOHNSON & JOHNSON CLIN DIAG (US) 2000-11-22 — — EP disclosed
EP-0699905-B1 Leuco dye coating compositions JOHNSON & JOHNSON CLIN DIAG (US) 2000-05-17 — — EP disclosed
EP-0603954-B1 Immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer JOHNSON & JOHNSON CLIN DIAG (US) 2000-03-08 — — EP disclosed
EP-0903583-A2 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements Ortho-Clinical Diagnostics, Inc. (US) 1999-03-24 — — EP disclosed
EP-0603962-B1 Immunoassay elements having a separate receptor layer JOHNSON & JOHNSON CLIN DIAG (US) 1999-02-17 — — EP disclosed
US-5714340-A LAYER CONTAINING LABELED LIGAND, BEAD SPREADING LAYER, CROSSLINKED HYDROPHILIC POLYMER LAYER AND A SUPPORT JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1998-02-03 — — US disclosed
US-5696193-A WATER SOLUBLE POLYMER; SPREADING LAYER ON IMMUNOASSAYANALYTICAL ELEMENT CLINICAL DIAGNOSTIC SYSTEMS, INC. (US) 1997-12-09 — — US disclosed
US-5516645-A Immunoassay analytical elements containing vanadium IV(V+4)ions JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-05-14 — — US disclosed
US-5496702-A TRIARYLIMIDAZOLE DYES, NONIONIC SURFACTANTS JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-03-05 — — US disclosed
EP-0684473-A2 Immunoassay elements comprising polymers containing vanadium IV (V (+4)) ions Johnson & Johnson Clinical Diagnostics, Inc. (US) 1995-11-29 — — EP disclosed
EP-0603962-A1 Immunoassay elements having a seperate receptor layer Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-06-29 — — EP disclosed
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