Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.70 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.69 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.59 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.48 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759436 | 1.00 | CYP1A2 (0.70) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL5351119 | 0.99 | CYP1A2 (0.71) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL5351115 | 0.99 | CYP1A2 (0.71) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL9273205 | 0.93 | PRMT1 (0.73) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL11791675 | 0.93 | PRMT1 (0.73) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL9273197 | 0.93 | PRMT1 (0.73) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL2161281 | 0.91 | PRMT1 (0.74) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL3042237 | 0.91 | PRMT1 (0.74) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL29399950 | 0.90 | PRMT1 (0.73) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 | |
| SCHEMBL186093 | 0.88 | PHLPP2 (0.68) | CYP1A2PRMT1CYP2C9MAPK1DNASE1L3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122572-B2 | For use in Hydrogen Bonding Liquid Chromatography, environmental remediation by removal of undesired ions or neutral molecules, removal of phosphate for kidney dialysis, drug delivery, separation | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2006-10-17 | — | — | US | disclosed |
| US-7041819-B2 | Halogenated calixpyrroles and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-05-09 | — | — | US | disclosed |
| US-6984734-B2 | Cyclo[n]pyrroles and methods thereto | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-01-10 | — | — | US | disclosed |
| US-20030229131-A1 | Cyclo[n]pyrroles and methods thereto | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2003-12-11 | — | — | US | disclosed |
| WO-2003072581-A1 | CYCLO[N]PYRROLES AND METHODS THERETO | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2003-09-04 | — | — | WO | disclosed |
| WO-2003018548-A2 | HALOGENATED CALIXPYRROLES, CALIXPYRIDINOPYRROLES AND CALIXPYRIDINES, AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2003-03-06 | — | — | WO | disclosed |
| US-20020115566-A1 | Halogenated calixpyrroles, calixpyridinopyrroles and calixpyridines, and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-08-22 | — | — | US | disclosed |
| US-20020026047-A1 | Calixpyrroles, calixpyridinopyrroles, and calixpyridines | BOARD OF REGENTS, THE | 2002-02-28 | — | — | US | disclosed |
| US-6262257-B1 | SELECTIVE ION- AND NEUTRAL MOLECULE-BINDING AGENTS FORMING SUPRAMOLECULAR ENSEMBLES, AND ION- AND NEUTRAL MOLECULE-SEPARATION AGENTS | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM | 2001-07-17 | — | — | US | disclosed |
| EP-0891364-A1 | CALIXPYRROLES, CALIXPYRIDINOPYRROLES AND CALIXPYRIDINES | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997037995-A1 | CALIXPYRROLES, CALIXPYRIDINOPYRROLES AND CALIXPYRIDINES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1997-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229131-A1 | Cyclo[n]pyrroles and methods thereto | PPOX, QPCT, PPIE | CYP1A2 1695/4885PRMT1 1070/4885CYP2C9 869/4885 |
| US-20020115566-A1 | Halogenated calixpyrroles, calixpyridinopyrroles and calixpyridines, and uses thereof | CALD1, CALU, CLASP1 | CYP1A2 2249/4885PRMT1 1205/4885CYP2C9 1174/4885 |
| US-20020026047-A1 | Calixpyrroles, calixpyridinopyrroles, and calixpyridines | CALD1, DAP3, CALR | CYP1A2 3644/4885PRMT1 303/4885CYP2C9 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.