Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135807 | 0.77 | HPGD (0.44) | MAPTHSD17B10MEN1POLBKMT2A | |
| SCHEMBL5918216 | 0.75 | FABP6 (0.52) | PIN1MAPTEGLN1HSD17B10LMNA | |
| SCHEMBL1258540 | 0.73 | EGLN1 (0.57) | PIN1EGLN1GRIN2DGRIN3BLMNA | |
| SCHEMBL1132610 | 0.69 | MAPT (0.62) | MAPTHRH4XDHLMNAMEN1 | |
| SCHEMBL28870254 | 0.69 | PLAU (0.54) | PIN1HRH4POLB | |
| SCHEMBL26241758 | 0.69 | PIN1 (0.57) | PIN1MAPTHRH4XDHHSD17B10 | |
| SCHEMBL23683140 | 0.69 | SMN1; SMN2 (0.40) | PIN1MAPTXDHHSD17B10LMNA | |
| Chloromethane SCHEMBL29246404 | 0.68 | MAPT (0.60) | MAPTHRH4XDHLMNAMEN1 | |
| SCHEMBL8071539 | 0.68 | HRH4 (0.60) | PIN1EGLN1HRH4HRH3MPO | |
| SCHEMBL8071535 | 0.68 | HRH4 (0.47) | PIN1MAPTHRH4HRH3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051898-A1 | UNUSUAL NUCLEOSIDE LIBRARIES, COMPOUNDS, AND PREFERRED USES AS ANTIVIRAL AND ANTICANCER AGENTS | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |