Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7076632 | 0.97 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7127467 | 0.94 | KDM4E (0.48) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7075764 | 0.92 | HSD17B10 (0.48) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7075468 | 0.89 | HSD17B10 (0.43) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7071974 | 0.89 | HSD17B10 (0.47) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7073292 | 0.88 | KDM4E (0.45) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7076651 | 0.87 | KDM4E (0.46) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7073531 | 0.86 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7073477 | 0.86 | CA12 (0.43) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7075479 | 0.85 | HSD17B10 (0.42) | HSD17B10KDM4EALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | disclosed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | ITGAV, ITGB2, ITGB3 | HSD17B10 3835/4885KDM4E 560/4885ALDH1A1 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.