Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 8/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 7/20 | 0.32 |
| ▸ | MTAP | Q13126 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070778 | 1.00 | PNP (0.39) | PNPTRPV3MTAP | |
| SCHEMBL7075461 | 1.00 | PNP (0.39) | PNPTRPV3MTAP | |
| SCHEMBL7071084 | 1.00 | PNP (0.39) | PNPTRPV3MTAP | |
| SCHEMBL7103658 | 0.92 | PNP (0.43) | PNPTRPV3MTAP | |
| SCHEMBL8066558 | 0.80 | CHEK1 (0.35) | TRPV3 | |
| SCHEMBL8062440 | 0.80 | CHEK1 (0.35) | TRPV3 | |
| SCHEMBL7652028 | 0.76 | PNP (0.39) | PNPTRPV3 | |
| SCHEMBL7070308 | 0.75 | — | — | |
| SCHEMBL7074549 | 0.75 | — | — | |
| SCHEMBL7072631 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001942-B1 | POLYHYDROXYBUTYLPYRAZINES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-06-25 | — | — | EP | claimed |
| US-6288066-B1 | ANTIDIABETIC AGENTS; OXIDATION, HYDROLYSIS | AVENTIS PHARMA S.A. (FR) | 2001-09-11 | — | — | US | claimed |
| EP-1001942-B1 | POLYHYDROXYBUTYLPYRAZINES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-06-25 | — | — | EP | disclosed |
| US-6288066-B1 | ANTIDIABETIC AGENTS; OXIDATION, HYDROLYSIS | AVENTIS PHARMA S.A. (FR) | 2001-09-11 | — | — | US | disclosed |