SCHEMBL7072595

SCHEMBL7072595

C=CC/C=C(\C)CC/C=C(\C)CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LSS P48449 3/20 0.39
ALOX15 P16050 2/20 0.38
KMT2A Q03164 2/20 0.34
BTN3A1 O00481 4/20 0.33
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
UGT1A1 P22309 1/20 0.32
FNTA P49354 3/20 0.32
FNTB P49356 3/20 0.32
SQLE Q14534 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6883980 0.83 KMT2A (0.50) LSSALOX15KMT2ABTN3A1MAPT
SCHEMBL6883983 0.83 KMT2A (0.50) LSSALOX15KMT2ABTN3A1MAPT
SCHEMBL31236120 0.83 KMT2A (0.50) LSSALOX15KMT2ABTN3A1MAPT
SCHEMBL14959289 0.83 KMT2A (0.35) LSSALOX15KMT2ABTN3A1MAPT
SCHEMBL9421307 0.82 FNTA (0.38) ALOX15KMT2ABTN3A1MAPTALDH1A1
SCHEMBL7072799 0.82 KMT2A (0.36) LSSALOX15KMT2ABTN3A1MAPT
SCHEMBL6765570 0.81 SQLE (0.44) LSSALOX15KMT2ABTN3A1MAPT
SCHEMBL9421365 0.78 HPGD (0.41) KMT2ABTN3A1FNTAFNTBSQLE
SCHEMBL9421299 0.77 ALDH1A1 (0.56) ALOX15BTN3A1ALDH1A1FNTAFNTB
SCHEMBL14959357 0.77 ALDH1A1 (0.56) ALOX15BTN3A1ALDH1A1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1158995-B1 BIOLOGICALLY ACTIVE COMPOUNDS OF GANODERMA PFEIFFERI DMS 13239 GANOMYCIN GES FUER BIOMEDIZINI (DE) 2003-06-18 EP disclosed
EP-1158995-A1 BIOLOGICALLY ACTIVE COMPOUNDS OF GANODERMA PFEIFFERI DMS 13239 Ganomycin Gesellschaft für Biomedizinische Forschung mbH (DE) 2001-12-05 EP disclosed
WO-2000053207-A1 BIOLOGICALLY ACTIVE COMPOUNDS OF $I(GANODERMA PFEIFFERI) DMS 13239 GANOMYCIN GESELLSCHAFT FÜR BIOMEDIZINISCHE FORSCHUNG MBH ; (DE) 2000-09-14 WO disclosed