Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7067878 | 0.99 | NMT1 (0.43) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7069528 | 0.93 | MMP13 (0.41) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7070604 | 0.91 | MAPT (0.44) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7070114 | 0.91 | NMT1 (0.42) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7065980 | 0.88 | MAPT (0.41) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7068896 | 0.87 | MAPT (0.47) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7070398 | 0.87 | MAPT (0.42) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7069279 | 0.86 | PPARA (0.45) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7068853 | 0.86 | MAPT (0.46) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL7070064 | 0.86 | MAPT (0.42) | NMT1MAPTSMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | MITSUI CHEMICALS, INC. (JP) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | PPARG, PPARD, PPARA | NMT1 2241/4885MAPT 2433/4885SMN1; SMN2 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.