Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633509 | 0.76 | — | — | |
| SCHEMBL6882418 | 0.76 | ALOX5 (0.41) | ALOX5ADRA1DNPC1RAB9APKM | |
| SCHEMBL2720668 | 0.71 | NPC1 (0.38) | ALOX5ADRA1DNPC1RAB9APKM | |
| SCHEMBL827163 | 0.69 | — | — | |
| SCHEMBL6315132 | 0.68 | ALOX5 (0.41) | ALOX5ADRA1DNPC1RAB9APKM | |
| SCHEMBL14923162 | 0.67 | — | — | |
| SCHEMBL9639925 | 0.67 | ALOX5 (0.51) | ALOX5ADRA1DNPC1RAB9AL3MBTL1 | |
| SCHEMBL11202396 | 0.66 | — | — | |
| SCHEMBL11151827 | 0.66 | — | — | |
| SCHEMBL19122447 | 0.66 | ALOX5 (0.46) | ALOX5ADRA1DNPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055479-A1 | COMPOUNDS AND THEIR THERAPEUTIC USE RELATED TO THE PHOSPHORYLATING ACTIVITY OF THE ENZYME GSK-3 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2003-07-10 | — | — | WO | disclosed |