Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | PLD1 | Q13393 | 5/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | BCL3 | P20749 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PLD2 | O14939 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078371 | 0.90 | CRBN (0.44) | PLD1CRBNBCL3ALDH1A1PLD2 | |
| SCHEMBL7774070 | 0.87 | PLD1 (0.44) | KDM4EPLD1BCL3ALDH1A1GAA | |
| SCHEMBL7074973 | 0.86 | KDM4E (0.44) | KDM4EPLD1BCL3ALDH1A1HPGD | |
| SCHEMBL8882719 | 0.84 | HPGD (0.52) | PLD1HPGD | |
| SCHEMBL7774077 | 0.83 | PLD1 (0.53) | PLD1ALDH1A1PLD2 | |
| SCHEMBL7781108 | 0.82 | PLD1 (0.53) | PLD1PLD2 | |
| SCHEMBL8876709 | 0.82 | EPHX2 (0.41) | PLD1BCL3PLD2 | |
| SCHEMBL8989699 | 0.81 | PLD1 (0.56) | PLD1ALDH1A1PLD2 | |
| Cyclopropane SCHEMBL7076457 | 0.79 | PLD1 (0.41) | PLD1PLD2KMT2A | |
| Cyclopentane SCHEMBL7071125 | 0.79 | PLD1 (0.41) | PLD1PLD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740658-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |