Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL3 | P20749 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075387 | 0.90 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAADRA1BHPGD | |
| SCHEMBL7774070 | 0.89 | PLD1 (0.44) | KDM4EALDH1A1PLD1HPGDBCL3 | |
| SCHEMBL8882719 | 0.86 | HPGD (0.52) | PLD1KDM1AHPGD | |
| SCHEMBL7073105 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1PLD1HPGDBCL3 | |
| SCHEMBL7774077 | 0.85 | PLD1 (0.53) | ALDH1A1PLD1KDM1A | |
| SCHEMBL7781108 | 0.84 | PLD1 (0.53) | PLD1KDM1A | |
| SCHEMBL8876709 | 0.83 | EPHX2 (0.41) | LMNAPLD1ADRA1BKDM1ABCL3 | |
| SCHEMBL8989699 | 0.83 | PLD1 (0.56) | ALDH1A1PLD1KDM1A | |
| Cyclopropane SCHEMBL7076457 | 0.81 | PLD1 (0.41) | PLD1 | |
| Cyclopentane SCHEMBL7071125 | 0.81 | PLD1 (0.41) | PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740658-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0740658-A1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995015312-A1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-08 | — | — | WO | disclosed |