Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | PLD2 | O14939 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentane SCHEMBL7071125 | 1.00 | PLD1 (0.41) | PLD1SIGMAR1PLD2CD274TSHR | |
| Cyclopropane SCHEMBL7076457 | 1.00 | PLD1 (0.41) | PLD1SIGMAR1PLD2CD274TSHR | |
| Cyclopentane SCHEMBL7071122 | 0.88 | ALDH1A1 (0.43) | SIGMAR1CD274 | |
| Cyclohexane SCHEMBL7076604 | 0.88 | ALDH1A1 (0.43) | SIGMAR1CD274 | |
| SCHEMBL7781108 | 0.87 | PLD1 (0.53) | PLD1PLD2CD274 | |
| SCHEMBL8877045 | 0.87 | ALDH1A1 (0.42) | SIGMAR1TSHRMEN1KMT2A | |
| SCHEMBL7774077 | 0.86 | PLD1 (0.53) | PLD1PLD2CD274 | |
| SCHEMBL8876300 | 0.85 | GLA (0.41) | PLD1SIGMAR1TSHRMEN1KMT2A | |
| SCHEMBL8877780 | 0.85 | KMT2A (0.41) | PLD1SIGMAR1TSHRMEN1KMT2A | |
| SCHEMBL8989699 | 0.84 | PLD1 (0.56) | PLD1PLD2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740658-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |