Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isatin SCHEMBL30956357 | 0.98 | MAPT (0.46) | MAPTKMT2AALDH1A1MEN1POLB | |
| Isatin SCHEMBL28827543 | 0.92 | MAPT (0.43) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL29161382 | 0.76 | MAPT (0.54) | MAPTKMT2AALDH1A1MEN1POLB | |
| Isatin SCHEMBL2293849 | 0.76 | KMT2A (0.36) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL28728640 | 0.74 | MAPT (0.41) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL9139763 | 0.73 | ATM (0.41) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL1137916 | 0.73 | MAPT (0.40) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL5855550 | 0.73 | MAPT (0.40) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL4365224 | 0.72 | MAPT (0.41) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL28576366 | 0.72 | MAPT (0.41) | MAPTKMT2AALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241809-A | Foaming polyurethane heat insulation material containing neutral water and preparation method thereof | 河北雄沃防火科技有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-118221564-A | Preparation method of branched-chain alcohol-containing hydroxy indolone | 滁州学院 | 2024-06-21 | — | — | CN | claimed |
| CN-111423351-B | Chiral copper compound and preparation method and application thereof | 中国科学技术大学 | 2024-03-29 | — | — | CN | claimed |
| CN-113149888-B | Hydroxy indolone derivative and preparation method and application thereof | 中山大学 | 2023-03-03 | — | — | CN | claimed |
| CN-113149888-A | Hydroxy indolone derivative and preparation method and application thereof | 中山大学 | 2021-07-23 | — | — | CN | claimed |
| CN-111423351-A | Chiral copper compound and preparation method and application thereof | 中国科学技术大学 | 2020-07-17 | — | — | CN | claimed |
| CN-102358729-A | 3-hydroxy- indol-2-one derivatives, anti-plant virus disease drugs adopting 3-hydroxy-indol-2-one derivatives as active ingredients, and application thereof | KUNMING INST BOTANY CN ACAD | 2012-02-22 | — | — | CN | claimed |
| JP-8333336-A | — | — | None | — | — | JP | disclosed |
| CN-119615198-A | Electrocatalytic oxidation modification method for indole skeleton-containing compound | 浙江工业大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-119264032-A | Preparation method of 3-hydroxy-2-indolone compound | 苏州大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-119241809-A | Foaming polyurethane heat insulation material containing neutral water and preparation method thereof | 河北雄沃防火科技有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-117447384-B | Spiro heterocyclic aryl compound and application thereof | 四川大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-118878450-A | C3-trifluoropropionyl oxydation reaction of N-substituted indole | 湖南科技职业学院 | 2024-11-01 | — | — | CN | disclosed |
| WO-2002066426-A2 | FLUORO OXINDOLE DERIVATIVES AS MODULATORS OF KCNQ POTASSIUM CHANNELS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-29 | — | — | WO | disclosed |
| EP-0747354-B1 | 3-Substituted oxindole derivatives as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998040504-A1 | METHODS FOR ALTERING BENZOXAZINONE LEVELS IN PLANTS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1998-09-17 | — | — | WO | disclosed |
| US-5602169-A | USEFUL IN REDUCING NEURONAL DAMAGE DURING ISCHEMIC STROKE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| JP-H08333336-A | 3-SUBSTITUTED OXINDOLE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | BRISTOL MYERS SQUIBB CO | 1996-12-17 | — | — | JP | disclosed |
| EP-0747354-A1 | 3-Substituted oxindole derivatives as potassium channel modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5565483-A | ADMINISTERING AS THERAPY FOR ISCHEMIA, CONVULSIONS OR ASTHMA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-15 | — | — | US | disclosed |